Match Summary
The Red Devils' disappointing run of form continued at Leeds' fortress, but manager Ruben Amorim had his Brazilian forward to thank for the team not suffering even more damage against their old rivals.
Dominic Calvert-Lewin directed a first-half effort against the post for the in-form hosts before Brenden Aaronson applied a cool finish with a driven, 62nd-minute shot.
At that stage, Amorim was under intense scrutiny after his side had been held by struggling Wolves at Old Trafford earlier in the week.
Nevertheless, against a team who had two days less to prepare, the forward levelled three minutes later when he latched onto a pass from substitute the Dutchman and guided a finish underneath advancing home goalkeeper Lucas Perri.
It was only the South American's fourth Premier League goal since his big-money summer move and came at a time when Amorim is without several key attacking players due to a mix of fitness issues and international duty.
Not that you would expect Leeds to sympathise with that given their own tight schedule.
Noah Okafor forced a diving save out of visiting goalkeeper Senne Lammens with a spectacular overhead kick, and United heads were in hands when the Slovenian striker, who is struggling to make an impression, turned Zirkzee's cut-back wide from close range.
The goalscorer, who had a goal disallowed for offside much earlier in the match, also fired against a post late on.
The draw extends the home side's unbeaten run to seven games, their longest such streak since 2001, and takes them eight points clear of the drop zone.
For the visitors though, it was yet another opportunity to move into the Champions League places, albeit only for a short time, squandered.
With the AFCON reaching its latter stages, the United coach could be forgiven for hoping the participating nations make a pretty quick exit.
Existing injuries to captain Bruno Fernandes and England international Mason Mount only heightened the impact the unavailability of other forwards is having on the team's options.
It's not that the missing pair are the solution to all of United's problems. After all, they were part of the side that suffered disappointing results earlier in the season.
But without them, Amorim has limited alternatives in attack.
He evidently does not trust teenager Shea Lacey or the much more experienced Zirkzee, even though the Netherlands forward provided the through ball for Cunha's equaliser almost instantly after his arrival as a replacement.
That leaves Cunha, who has now scored a small tally in five games, and others playing out of their preferred positions, alongside Benjamin Sesko.
On this showing, the expensive frontman looks similar to previous struggling signings, lacking in confidence and conviction in front of goal.
His failure to turn home the cross means it is now nine games without a goal for the young striker.
After thrilling victories in their previous home games, the arrival of their fiercest rivals to home was a bit drab affair.
True, there were instances of typical fervor, but the intimidating edge was not as pronounced as in previous fixtures.
The home fans were more preoccupied about their side's inability to get worthwhile possession in advanced areas for any prolonged period.
The striker's header that clipped the post was an isolated moment of quality in a congested first half.
It still felt as though the hosts were finding it tough when a defensive error opened the door for Aaronson.
For a short moment, The home ecstatic fans thought they were about to secure a coveted win against Manchester United.
However, there is a wider context for the manager and the club to deal with.
When they endured a poor run of form earlier in the campaign, many thought about the manager's position.
Instead, he is now overseeing significant improvement.
The job is not done yet but gradually, Leeds are getting closer to achieving their top-flight status.
Leeds have a Premier League trip to St James' Park in midweek, followed by the start of their FA Cup campaign next weekend. The Red Devils face a Premier League trip to Turf Moor before also entering their cup journey with a home tie.
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Brenda Key